Oral Soluble Films: The safest option for your medication
With an increase in the number of infant and senior citizen population, the traditional drug delivery systems are not yielding great results. The non-acceptance rate of tablets and capsules is on the rise, and even if they are forcibly administered to patients, the non like worthiness of these systems may cause an emotional breakdown in them. The challenge is to innovate a new mechanism to inject the drugs and also not to compromise on the safety which is a paramount concern. Nagpur-based ZIM Laboratories gives a glimmer of hope with its novel drug delivery systems (NDDS) that acts like a boon for the population in the age group of 0-5 and above 60 years.
The 30 Year ZIM Legacy
Zim Laboratories brings its 3-decade long expertise as innovative Healthcare solution providers in developing Oral Soluble films – the easiest and safest option for medication. Zim has researched a lot on the formation of films to make them safe and non-invasive. Thus resulted in Oral Soluble Films that are the safest option for medication.
Choosing the Right excipient
Zim with its comprehensive understanding of low dose and high dose drugs chooses the right excipient by evaluating its safety and toxicity levels before its use in the film formation. The daily recommended dose for excipients is established and the intake has to be as per the set guidelines. So there are no chances or overdose and the necessary checks and measures are taken in this respect. Zim effectively uses the taste masking technique so that the drugs are not rejected or discarded by non-compliant patients.
Following the Regulation Checklist
In the US FDA, a complete database of inactive ingredients is established and followed in every drug product. Zim laboratories strictly adhere to these practices and manufacture Oral soluble films as per the global standards. The regulations are followed for a single drug product, but if a patient is prescribed more than one drug product, there are chances that the dose of excipients may exceed its recommended levels. With the Drug regulatory agencies becoming stricter in the control of excipients that support the pharmaceutical formulation, Zim is taking up best practices and going beyond the conventional approach to making drugs.
OSF has a high drug acceptance rate
Oral soluble films are the elegant, thin films that weigh much less than its corresponding tablet, capsule, syrup or suspension dosage form. The lesser weight of OSF is due to the low weight of excipients. When OSF is co-prescribed with other medicines, it makes the therapy safer. OSF scores higher than many of its predecessors owing to their ease of storage and ingestion. Once the strip gets into the oral cavity the soluble nature prevents it from rejection or discardment from infants and patients from other age groups. This increases the drug acceptance rate and checks all the boxes of safety.
Innovation & Awards
Innovation is the middle name of Zim Laboratories. When the company identified the need for an oral soluble film, it ensured non-stickiness to the strip so that it passes through the inner surface of the mouth. The big challenge was to bring stickiness to the substance when the film was placed in the desired location. Zim managed to pull off a tight rope walk with its research and gave the world a unique film that sticks to avoid the patient spitting it and doesn’t stick to give it a safe passage inside the oral cavity. That’s no less than a wonder!
This innovation got ZIM Laboratories the award for Best Innovation Development of a solid dosage form for the year 2016 by India Pharmaceutical Association.
About ZIM Laboratories
ZIM is an innovative drug delivery solution provider focusing on improving patient convenience and adherence to drug intake. We offer a range of technology-based drug delivery solutions and non-infringing proprietary manufacturing processes for production and supply of innovative and differentiated generic pharmaceutical products to our customers globally. ZIM provides its customers with a comprehensive range of value-added solid dosage differentiated generic products in semi-finished and finished categories/formulations. These include granules, pellets (sustained, modified, extended-release), taste-masked powders, suspensions, tablets, capsules and its recently developed Oral Thin Films (OTF)