The new drug delivery system set to revolutionise the pharma industry.
ORAL THIN FILMS
ORAL THIN FILMS
THINORAL TECHNOLOGY
Oral Thin Films (OTF) is the latest addition to ZIM's stable.
It is one of the few companies globally and one of the very few companies in India to have mastered the OTF technology.
ZIM Oral Thin Film (OTF) Technology is patented as Thinoral® with about 19 applied product/proccess patents for oral films globally.
It has received 24 DCGI product approvals & is awaiting 14 in India and 13 product approvals overseas.
Its rapidly dissolving, non-sticky films have a drug loading capacity as high as 100 mg of the active drug. The faster release profile alleviates solubility issues in poorly soluble drugs.
Unlike orally disintegrating tablets that are manufactured using lyophilisation or low compression pressure, the Thinoral® strips are flexible and offer ease of storage and transportation.
Thinoral® technology could also be used for delivery of drugs through sublingual and buccal absorption routes, showing improved bioavailability by avoiding first pass metabolism.
OTF BUSINESS GROWTH
Several OTF products have already been out-licensed to major pharmaceutical companies. More are under discussion with key pharma players and also under own registration in several markets.
ZIM has developed 19 products and commercialized 13 of them within 3 years Technology developed is indigenous consisting of equipment design (manufacturing and testing) as well as formulation development resulting in a manufacturing system capable of high throughput commercial output of high quality oral films.
OTF DISPERSION FORMS
ZIM has filed 37 patents Registered over 170 formulations in various markets (mainly RoW).
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