The new drug delivery system set to revolutionise the mode of drug administration.
Conventional oral solid dosage forms like tablets and capsules, despite their several advantages and resultant popularity, suffer from one great disadvantage, that is they have to be swallowed preferably with water or any other liquid. Voluntary swallowing is a hindrance in drug administration for children, elderly, mentally challenged, nauseated, unconscious and bedridden patients.
A need for non-obstructive dosage form possessing the other advantages of tablets has been felt constantly by the physicians and patients for many years. The concept of oral thin film as drug-delivering dosage forms evolved as an answer to the need for this special need patient population.
Introducing Thinoral Technology
ORAL THIN FILM: A UNIQUE DRUG DELIVERY SYSTEM
Our Patented Thinoral® technology for manufacturing thin films yields instantly wettable, rapidly dissolving, non-sticky, non-tacky and non-curving films with drug loading, as high as 100 mg of the active drug. These films, when placed on the tongue, get wetted by saliva, adhere to the tongue mucosa and disintegrate almost instantaneously. The fast dissolving feature of the film is appreciated by consumers and physicians alike.
The technology is also suitable for the delivery of drugs through sublingual and buccal route, showing improved bioavailability by avoiding first® pass metabolism. Even nanotechnology based formulations have been designed using the Thinoral® technology platform that retains all the desired product attributes.
Oral Thin Films (OTF) is the latest addition to ZIM Labs stable.
It is one of the few companies globally and one of the very few companies in India to have mastered the OTF technology.
ZIM Labs Oral Thin Film (OTF) Technology is patented as Thinoral® with about 19 applied product/proccess patents for oral films globally.
With more than 100 registration in various semi-regulated and regulated markets, patented Thinoral technology is getting wider acceptance.
Its rapidly dissolving, non-sticky films have a drug loading capacity as high as 100 mg of the active drug. The faster release profile alleviates solubility issues in poorly soluble drugs.
Unlike orally disintegrating tablets that are manufactured using lyophilisation or low compression pressure, the Thinoral® strips are flexible and offer ease of storage and transportation.
Thinoral® technology could also be used for delivery of drugs through sublingual and buccal absorption routes, showing improved bioavailability by avoiding first pass metabolism.
The Thinoral® technology is protected by more than 30 patent applications filed worldwide out of which some are already granted in US and India.