The Importance of Medicine Acceptance Among Pediatric Patients

April 4, 2023

Children are the fussiest eaters and can be the most difficult age group for administering any drug. Not only do their rapid movements and crying make the drug delivery very difficult, but the risk of choking or the medicine entering the windpipe is also increased in cases of oral tablets.This is why it was thought necessary by the pharmaceutical pellets manufacturers in India to devise solutions that make administering doses to children a lot easier!

Factors That Affect Medicine Acceptance Among Children:

The Taste:

Taste of the medicine is one of the primary reasons children refrain from taking medicines altogether. The truth is that most medicines have a very bitter or unpalatable taste. The adults realize the importance of the medicines and have them, but the children refuse to take them many times. The displeasure they received from the unpalatable test resulted in the spitting of the medication or even resulted in nausea in the children

The Size Of The Tablet:

The adults can swallow an average-sized tablet, but the child may not be able to do so. This may be due to two reasons- firstly, they have a narrower food pipe than the adults, and secondly, they do not know the technique of swallowing the medicine properly. Either way, the tablet becomes a choking hazard for the child and may cause serious problems in the case of some specially-abled children.

Inappropriate Dosage:

Considering that a lot of the medication may be spilled while delivering the syrups or solutions, rarely can the correct dosage of a drug be ever administered to the child. In some cases, if the child gets hold of the medicine, the chances of overdose also cannot be neglected.

How can drugs be made more palatable to children:

It has been a challenge for the health care providers as well as the parents to be able to administer the right dosage of medication to the children. You are some of the ways how drugs can be made more palatable to children:

  • The solution of the medicine can be given to the children via a dropper dropping the liquid at the back of their mouth close to the throat to avoid the tongue from perceiving the taste
  • Some flavors might be added to the liquids to make them taste better and marks that taste.
  • Something like a layer of peanut butter or a peppermint candy may be given before giving the medication if possible so that the tongue already has an overwhelming flavor and the flavor of the medicine does not seem that pronounced
  • The pill can be covered with something that you are child likes and then administered
  • Check with your doctor to find out if the pill can be dissolved in water and put a little bit of sweetener in it to make it more palatable
  •  Mashing the pill into any soft pudding or eatable is also possible, but it is advised to ask your doctor before doing so.

Multiparticulates - An Overview

Multi particulates are those drug delivery systems introduced in the body, and the dosage of drug administration can be controlled with the help of pulsations or programming. Many drugs can also be compiled into 1 multiparticulate system and released into the body at regular controlled intervals. The active substance is present as several small independent subunits. Нence, they provide many advantages over single-unit systems because of their small size.

How Multiparticulate Formulations Can Be Used To Develop Drugs For Pediatric Patients

The best thing about these formulations is that they do not need to be taken as frequently as normal drugs. Many of the different pharmaceutically active ingredients can be packed into the little capsule and programmed to release at certain time intervals individually. These tablets are so small that the child can easily consume them without the need for water, and they are also tasteless, which makes them palatable.

Benefits of multiparticulates:

1. Good stability that prevents overdose

2. Accurate dosage that does not need to be regularly monitored

3. Small packing size for easy intake

4. Minimal risk of suffocation because of the small size

5. No need for water


Multi particulates can, therefore, revolutionize the way drugs are administered to children, making them very convenient for consumption and more effective.

About ZIM Laboratories:

ZIM Labs is an innovative drug delivery solution provider focusing on improving patient convenience and adherence to drug intake. We offer a range of technology-based drug delivery solutions and non-infringing proprietary manufacturing processes to produce and supply innovative and differentiated generic pharmaceutical products to our customers globally. At ZIM Labs, we provide our customers with a comprehensive range of solid value-added dosage differentiated generic products in semi-finished and finished categories/formulations. These include granules, pellets (sustained, modified, extended-release), taste-masked powders, suspensions, tablets, capsules, and recently developed Oral Thin Films (OTF).


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